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Hypertension in Women: Should There be a Sex-specific Threshold?
Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger ri...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Radcliffe Cardiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548871/ https://www.ncbi.nlm.nih.gov/pubmed/34733358 http://dx.doi.org/10.15420/ecr.2021.17 |
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author | Gerdts, Eva de Simone, Giovanni |
author_facet | Gerdts, Eva de Simone, Giovanni |
author_sort | Gerdts, Eva |
collection | PubMed |
description | Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger risk factor for cardiovascular disease (CVD) in women than men. While healthy young women have lower BP than men, a steeper increase in BP is found in women from the third decade of life. Studies have documented that the BP-attributable risk for acute coronary syndromes (ACS), heart failure and AF increases at a lower level of BP in women than in men. Even high normal BP (130–139/80–89 mmHg) is associated with an up to twofold higher risk of ACS during midlife in women, but not in men. Whether sex-specific thresholds for definition of hypertension would improve CVD risk detection should be considered in future guidelines for hypertension management and CVD prevention. |
format | Online Article Text |
id | pubmed-8548871 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Radcliffe Cardiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-85488712021-11-02 Hypertension in Women: Should There be a Sex-specific Threshold? Gerdts, Eva de Simone, Giovanni Eur Cardiol Women and Heart Disease Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger risk factor for cardiovascular disease (CVD) in women than men. While healthy young women have lower BP than men, a steeper increase in BP is found in women from the third decade of life. Studies have documented that the BP-attributable risk for acute coronary syndromes (ACS), heart failure and AF increases at a lower level of BP in women than in men. Even high normal BP (130–139/80–89 mmHg) is associated with an up to twofold higher risk of ACS during midlife in women, but not in men. Whether sex-specific thresholds for definition of hypertension would improve CVD risk detection should be considered in future guidelines for hypertension management and CVD prevention. Radcliffe Cardiology 2021-10-18 /pmc/articles/PMC8548871/ /pubmed/34733358 http://dx.doi.org/10.15420/ecr.2021.17 Text en Copyright © 2021, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly. |
spellingShingle | Women and Heart Disease Gerdts, Eva de Simone, Giovanni Hypertension in Women: Should There be a Sex-specific Threshold? |
title | Hypertension in Women: Should There be a Sex-specific Threshold? |
title_full | Hypertension in Women: Should There be a Sex-specific Threshold? |
title_fullStr | Hypertension in Women: Should There be a Sex-specific Threshold? |
title_full_unstemmed | Hypertension in Women: Should There be a Sex-specific Threshold? |
title_short | Hypertension in Women: Should There be a Sex-specific Threshold? |
title_sort | hypertension in women: should there be a sex-specific threshold? |
topic | Women and Heart Disease |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548871/ https://www.ncbi.nlm.nih.gov/pubmed/34733358 http://dx.doi.org/10.15420/ecr.2021.17 |
work_keys_str_mv | AT gerdtseva hypertensioninwomenshouldtherebeasexspecificthreshold AT desimonegiovanni hypertensioninwomenshouldtherebeasexspecificthreshold |