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Hypertension in Women: Should There be a Sex-specific Threshold?

Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger ri...

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Detalles Bibliográficos
Autores principales: Gerdts, Eva, de Simone, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Radcliffe Cardiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548871/
https://www.ncbi.nlm.nih.gov/pubmed/34733358
http://dx.doi.org/10.15420/ecr.2021.17
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author Gerdts, Eva
de Simone, Giovanni
author_facet Gerdts, Eva
de Simone, Giovanni
author_sort Gerdts, Eva
collection PubMed
description Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger risk factor for cardiovascular disease (CVD) in women than men. While healthy young women have lower BP than men, a steeper increase in BP is found in women from the third decade of life. Studies have documented that the BP-attributable risk for acute coronary syndromes (ACS), heart failure and AF increases at a lower level of BP in women than in men. Even high normal BP (130–139/80–89 mmHg) is associated with an up to twofold higher risk of ACS during midlife in women, but not in men. Whether sex-specific thresholds for definition of hypertension would improve CVD risk detection should be considered in future guidelines for hypertension management and CVD prevention.
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spelling pubmed-85488712021-11-02 Hypertension in Women: Should There be a Sex-specific Threshold? Gerdts, Eva de Simone, Giovanni Eur Cardiol Women and Heart Disease Conventionally, hypertension is defined by the same blood pressure (BP) threshold (systolic BP ≥140 and/or diastolic BP ≥90 mmHg) in both women and men. Several studies have documented that women with hypertension are more prone to develop BP-associated organ damage and that high BP is a stronger risk factor for cardiovascular disease (CVD) in women than men. While healthy young women have lower BP than men, a steeper increase in BP is found in women from the third decade of life. Studies have documented that the BP-attributable risk for acute coronary syndromes (ACS), heart failure and AF increases at a lower level of BP in women than in men. Even high normal BP (130–139/80–89 mmHg) is associated with an up to twofold higher risk of ACS during midlife in women, but not in men. Whether sex-specific thresholds for definition of hypertension would improve CVD risk detection should be considered in future guidelines for hypertension management and CVD prevention. Radcliffe Cardiology 2021-10-18 /pmc/articles/PMC8548871/ /pubmed/34733358 http://dx.doi.org/10.15420/ecr.2021.17 Text en Copyright © 2021, Radcliffe Cardiology https://creativecommons.org/licenses/by-nc/4.0/This work is open access under the CC-BY-NC 4.0 License which allows users to copy, redistribute and make derivative works for non-commercial purposes, provided the original work is cited correctly.
spellingShingle Women and Heart Disease
Gerdts, Eva
de Simone, Giovanni
Hypertension in Women: Should There be a Sex-specific Threshold?
title Hypertension in Women: Should There be a Sex-specific Threshold?
title_full Hypertension in Women: Should There be a Sex-specific Threshold?
title_fullStr Hypertension in Women: Should There be a Sex-specific Threshold?
title_full_unstemmed Hypertension in Women: Should There be a Sex-specific Threshold?
title_short Hypertension in Women: Should There be a Sex-specific Threshold?
title_sort hypertension in women: should there be a sex-specific threshold?
topic Women and Heart Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8548871/
https://www.ncbi.nlm.nih.gov/pubmed/34733358
http://dx.doi.org/10.15420/ecr.2021.17
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