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Inactivation of the CB(2) receptor accelerated the neuropathological deterioration in TDP‐43 transgenic mice, a model of amyotrophic lateral sclerosis

The activation of the cannabinoid receptor type‐2 (CB(2)) afforded neuroprotection in amyotrophic lateral sclerosis (ALS) models. The objective of this study was to further investigate the relevance of the CB(2) receptor through investigating the consequences of its inactivation. TDP‐43(A315T) trans...

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Detalles Bibliográficos
Autores principales: Rodríguez‐Cueto, Carmen, Gómez‐Almería, Marta, García Toscano, Laura, Romero, Julián, Hillard, Cecilia J., de Lago, Eva, Fernández‐Ruiz, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549023/
https://www.ncbi.nlm.nih.gov/pubmed/33983653
http://dx.doi.org/10.1111/bpa.12972