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Role of VAPB and vesicular profiles in α‐synuclein aggregates in multiple system atrophy

The pathological hallmark of multiple system atrophy (MSA) is fibrillary aggregates of α‐synuclein (α‐Syn) in the cytoplasm and nucleus of both oligodendrocytes and neurons. In neurons, α‐Syn localizes to the cytosolic and membrane compartments, including the synaptic vesicles, mitochondria, and end...

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Detalles Bibliográficos
Autores principales: Mori, Fumiaki, Miki, Yasuo, Tanji, Kunikazu, Kon, Tomoya, Tomiyama, Masahiko, Kakita, Akiyoshi, Wakabayashi, Koichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549028/
https://www.ncbi.nlm.nih.gov/pubmed/34196429
http://dx.doi.org/10.1111/bpa.13001