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High expression levels and the C3435T SNP of the ABCB1 gene are associated with lower survival in adult patients with acute myeloblastic leukemia in Mexico City

BACKGROUND: Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy characterized by different genetic alterations that cause changes in the normal mechanisms of differentiation, which are associated with chemoresistance. The ABCB1 gene is part of a family of ATP-binding cassette (ABC...

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Detalles Bibliográficos
Autores principales:	Olarte Carrillo, Irma, García Laguna, Anel Irais, De la Cruz Rosas, Adrián, Ramos Peñafiel, Christian Omar, Collazo Jaloma, Juan, Martínez Tovar, Adolfo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549154/ https://www.ncbi.nlm.nih.gov/pubmed/34702282 http://dx.doi.org/10.1186/s12920-021-01101-y

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