MYSM1 inhibits human colorectal cancer tumorigenesis by activating miR-200 family members/CDH1 and blocking PI3K/AKT signaling

BACKGROUND: Histone epigenetic modification disorder is an important predisposing factor for the occurrence and development of many cancers, including colorectal cancer (CRC). The role of MYSM1, a metalloprotease that deubiquitinates monoubiquitinated histone H2A, in colorectal cancer was identified...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Wang, Wei, Li, Yufang, Huo, Yi, Zhang, Han, Feng, Fan, Xi, Wenjin, Zhang, Tianze, Gao, Jinjian, Yang, Fan, Chen, Siyi, Yang, Angang, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549173/
https://www.ncbi.nlm.nih.gov/pubmed/34706761
http://dx.doi.org/10.1186/s13046-021-02106-2

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