Cargando…

Secretome of endothelial progenitor cells from stroke patients promotes endothelial barrier tightness and protects against hypoxia-induced vascular leakage

BACKGROUND: Cell-based therapeutic strategies have been proposed as an alternative for brain repair after stroke, but their clinical application has been hampered by potential adverse effects in the long term. The present study was designed to test the effect of the secretome of endothelial progenit...

Descripción completa

Detalles Bibliográficos
Autores principales:	Loiola, Rodrigo Azevedo, García-Gabilondo, Miguel, Grayston, Alba, Bugno, Paulina, Kowalska, Agnieszka, Duban-Deweer, Sophie, Rizzi, Eleonora, Hachani, Johan, Sano, Yasuteru, Shimizu, Fumitaka, Kanda, Takashi, Mysiorek, Caroline, Mazurek, Maciej Piotr, Rosell, Anna, Gosselet, Fabien
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549346/ https://www.ncbi.nlm.nih.gov/pubmed/34702368 http://dx.doi.org/10.1186/s13287-021-02608-y

Ejemplares similares

Development of a human in vitro blood–brain tumor barrier model of diffuse intrinsic pontine glioma to better understand the chemoresistance
por: Deligne, Clémence, et al.
Publicado: (2020)

Highlighting In Vitro the Role of Brain-like Endothelial Cells on the Maturation and Metabolism of Brain Pericytes by SWATH Proteomics
por: Menaceur, Camille, et al.
Publicado: (2023)

Contribution of brain pericytes in blood–brain barrier formation and maintenance: a transcriptomic study of cocultured human endothelial cells derived from hematopoietic stem cells
por: Heymans, Marjolein, et al.
Publicado: (2020)

Targeting and Crossing the Blood-Brain Barrier with Extracellular Vesicles
por: Saint-Pol, Julien, et al.
Publicado: (2020)

Association of Endothelial Glycocalyx and Tight and Adherens Junctions With Severity of Plasma Leakage in Dengue Infection
por: Suwarto, Suhendro, et al.
Publicado: (2017)

TNAP and EHD1 Are Over-Expressed in Bovine Brain Capillary Endothelial Cells after the Re-Induction of Blood-Brain Barrier Properties
por: Deracinois, Barbara, et al.
Publicado: (2012)

A large-scale electrophoresis- and chromatography-based determination of gene expression profiles in bovine brain capillary endothelial cells after the re-induction of blood-brain barrier properties
por: Pottiez, Gwënaël, et al.
Publicado: (2010)

Serotonin/5-HT1A Signaling in the Neurovascular Unit Regulates Endothelial CLDN5 Expression
por: Sugimoto, Kotaro, et al.
Publicado: (2020)

Glycoproteomic Analysis of the Secretome of Human Endothelial Cells
por: Yin, Xiaoke, et al.
Publicado: (2013)

DENV NS1 and MMP-9 cooperate to induce vascular leakage by altering endothelial cell adhesion and tight junction
por: Pan, Pan, et al.
Publicado: (2021)

Inward Leakage in Tight-Fitting PAPRs
por: Koh, Frank C., et al.
Publicado: (2011)

Sex-dependent differences in the secretome of human endothelial cells
por: Cattaneo, Maria Grazia, et al.
Publicado: (2021)

TNFα Activates the Liver X Receptor Signaling Pathway and Promotes Cholesterol Efflux from Human Brain Pericytes Independently of ABCA1
por: Dib, Shiraz, et al.
Publicado: (2023)

Exploring the Mesenchymal Stem Cell Secretome for Corneal Endothelial Proliferation
por: Van den Bogerd, Bert, et al.
Publicado: (2020)

Endothelial Claudin: Claudin-5/Tmvcf Constitutes Tight Junction Strands in Endothelial Cells
por: Morita, Kazumasa, et al.
Publicado: (1999)

Comparative and Quantitative Global Proteomics Approaches: An Overview
por: Deracinois, Barbara, et al.
Publicado: (2013)

Endothelial tight junctions form the blood–brain barrier
por: Bonetta, Laura
Publicado: (2005)

β-Cyclodextrins Decrease Cholesterol Release and ABC-Associated Transporter Expression in Smooth Muscle Cells and Aortic Endothelial Cells
por: Coisne, Caroline, et al.
Publicado: (2016)

The Lymphatic Endothelial Cell Secretome Inhibits Osteoblast Differentiation and Bone Formation
por: Solorzano, Ernesto, et al.
Publicado: (2023)

The Secretome of Endothelial Progenitor Cells Promotes Brain Endothelial Cell Activity through PI3-Kinase and MAP-Kinase
por: Di Santo, Stefano, et al.
Publicado: (2014)

Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging
por: Salman, Mootaz M., et al.
Publicado: (2020)

The secretome of endothelial progenitor cells: a potential therapeutic strategy for ischemic stroke
por: Alwjwaj, Mansour, et al.
Publicado: (2021)

Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
por: Spampinato, Simona F., et al.
Publicado: (2015)

Role of endothelial microRNA 155 on capillary leakage in systemic inflammation
por: Etzrodt, Valerie, et al.
Publicado: (2021)

Pioglitazone Attenuates the Effects of Peripheral Inflammation in a Human In Vitro Blood–Brain Barrier Model
por: da Rocha, Gustavo Henrique Oliveira, et al.
Publicado: (2022)

Fibrogenic Secretome of Sirtuin 1-Deficient Endothelial Cells: Wnt, Notch and Glycocalyx Rheostat
por: Lipphardt, Mark, et al.
Publicado: (2018)

Analysis of Melanoma Secretome for Factors That Directly Disrupt the Barrier Integrity of Brain Endothelial Cells
por: Anchan, Akshata, et al.
Publicado: (2020)

Sustained neuronal viability by paracrine factors: new opportunities for endothelial progenitor cell secretome
por: Di Santo, Stefano, et al.
Publicado: (2020)

Advancing human induced pluripotent stem cell‐derived blood‐brain barrier models for studying immune cell interactions
por: Nishihara, Hideaki, et al.
Publicado: (2020)

Formyl Peptide Receptor Activation Elicits Endothelial Cell Contraction and Vascular Leakage
por: Wenceslau, Camilla F., et al.
Publicado: (2016)

Endothelial Microvesicles Induce Pulmonary Vascular Leakage and Lung Injury During Sepsis
por: Zheng, Danyang, et al.
Publicado: (2020)

Tight control – decision-making during T cell–vascular endothelial cell interaction
por: Firner, Sonja, et al.
Publicado: (2012)

Tight junction between endothelial cells: the interaction between nanoparticles and blood vessels
por: Zhang, Yue, et al.
Publicado: (2016)

Endothelial Progenitor Cell Migration-Enhancing Factors in the Secretome of Placental-Derived Mesenchymal Stem Cells
por: Kamprom, Witchayaporn, et al.
Publicado: (2016)

Secretome Analysis of Rabbit and Human Mesenchymal Stem and Endothelial Progenitor Cells: A Comparative Study
por: Vašíček, Jaromír, et al.
Publicado: (2021)

Deficiency of endothelial sirtuin1 in mice stimulates skeletal muscle insulin sensitivity by modifying the secretome
por: Li, Qiuxia, et al.
Publicado: (2023)

Secondary migration and leakage of methane from a major tight-gas system
por: Wood, James M., et al.
Publicado: (2016)

Endothelial transmigration hotspots limit vascular leakage through heterogeneous expression of ICAM‐1
por: Grönloh, Max L B, et al.
Publicado: (2022)

Pertussis Toxin Exploits Host Cell Signaling Pathways Induced by Meningitis-Causing E. coli K1-RS218 and Enhances Adherence of Monocytic THP-1 Cells to Human Cerebral Endothelial Cells
por: Starost, Laura Julia, et al.
Publicado: (2016)

Anthrax Lethal Toxin Downregulates Claudin-5 Expression in Human Endothelial Tight Junctions
por: D’Agnillo, Felice, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_qpvggeurofevku5oqgrdcqus02