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Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system

Hospital-associated infections (HAIs) are a major burden in healthcare systems. In this study, UVC LEDs emitting radiation from 260 to 270 nm were evaluated for effectiveness in reducing methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium and Acinetobacter b...

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Detalles Bibliográficos
Autores principales: Mariita, Richard M., Randive, Rajul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Microbiology Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549383/
https://www.ncbi.nlm.nih.gov/pubmed/34712901
http://dx.doi.org/10.1099/acmi.0.000194
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author Mariita, Richard M.
Randive, Rajul V.
author_facet Mariita, Richard M.
Randive, Rajul V.
author_sort Mariita, Richard M.
collection PubMed
description Hospital-associated infections (HAIs) are a major burden in healthcare systems. In this study, UVC LEDs emitting radiation from 260 to 270 nm were evaluated for effectiveness in reducing methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii . The array has four WD LEDs, each with 70 mW placed at 7 cm from test organisms. With 11.76 mJ cm(−2), the study obtained 99.99% reduction (log(10) reduction factor of 4) against MRSA and VRE. For A. baumannii , 9 mJ cm(−2) obtained 99.999% reduction (log(10) reduction factor of 5). These results present scientific evidence on how effective UVC LEDs can be used in the fight against HAIs.
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spelling pubmed-85493832021-10-27 Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system Mariita, Richard M. Randive, Rajul V. Access Microbiol Short Communications Hospital-associated infections (HAIs) are a major burden in healthcare systems. In this study, UVC LEDs emitting radiation from 260 to 270 nm were evaluated for effectiveness in reducing methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii . The array has four WD LEDs, each with 70 mW placed at 7 cm from test organisms. With 11.76 mJ cm(−2), the study obtained 99.99% reduction (log(10) reduction factor of 4) against MRSA and VRE. For A. baumannii , 9 mJ cm(−2) obtained 99.999% reduction (log(10) reduction factor of 5). These results present scientific evidence on how effective UVC LEDs can be used in the fight against HAIs. Microbiology Society 2021-09-15 /pmc/articles/PMC8549383/ /pubmed/34712901 http://dx.doi.org/10.1099/acmi.0.000194 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License.
spellingShingle Short Communications
Mariita, Richard M.
Randive, Rajul V.
Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system
title Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system
title_full Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system
title_fullStr Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system
title_full_unstemmed Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system
title_short Disinfection of methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus faecium and Acinetobacter baumannii using Klaran WD array system
title_sort disinfection of methicillin-resistant staphylococcus aureus, vancomycin-resistant enterococcus faecium and acinetobacter baumannii using klaran wd array system
topic Short Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549383/
https://www.ncbi.nlm.nih.gov/pubmed/34712901
http://dx.doi.org/10.1099/acmi.0.000194
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