Cargando…
Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review
OBJECTIVE: Aneurysmal bone cysts (ABCs) are blood-filled, locally destructive, benign bone tumors. Our objective was to conduct a systematic review outlining patient demographics, clinical characteristics, management, and outcomes of those with ABCs of the craniofacial bones. DATA SOURCES: Using Pub...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549472/ https://www.ncbi.nlm.nih.gov/pubmed/34723050 http://dx.doi.org/10.1177/2473974X211052950 |
_version_ | 1784590792155725824 |
---|---|
author | Rehman, Rafey Dekhou, Antonio Osto, Muhammad Agemy, Jacob Chaaban, Amneah Yuhan, Brian Thorpe, Eric |
author_facet | Rehman, Rafey Dekhou, Antonio Osto, Muhammad Agemy, Jacob Chaaban, Amneah Yuhan, Brian Thorpe, Eric |
author_sort | Rehman, Rafey |
collection | PubMed |
description | OBJECTIVE: Aneurysmal bone cysts (ABCs) are blood-filled, locally destructive, benign bone tumors. Our objective was to conduct a systematic review outlining patient demographics, clinical characteristics, management, and outcomes of those with ABCs of the craniofacial bones. DATA SOURCES: Using PubMed, Cochrane, and Embase databases, 116 studies were included. REVIEW METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, a systematic review was conducted. Data including patient demographics, clinical characteristics, treatment strategies, and patient outcomes were collected. RESULTS: A total of 127 patients from 116 studies were identified. Age ranged from 8 months to 90 years, with a mean age of 19.0 years. The most commonly affected craniofacial locations were the mandible (n = 31, 24.4%), temporal bone (n = 21, 16.5%), and occipital bone (n = 14, 11.0%). The most common presenting symptoms included a nontender mass (n = 51, 40.2%), a tender mass (n = 31, 24.4%), and generalized headache (n = 30, 23.6%). Imaging modalities included computed tomography (CT) and magnetic resonance imaging (MRI) (n = 77, 60.6%), CT alone (n = 31, 24.4%), and MRI alone (n = 8, 6.2%). All patients underwent surgical resection, with 1 patient requiring adjuvant radiation in addition to surgery. In total, 121 patients were disease-free and symptom-free without evidence of recurrence (17.4-month mean follow-up, 5.4 months average time to first recurrence). CONCLUSION: The current literature’s characterization of ABCs in craniofacial bones is limited to case reports and case series. Given the rarity of these tumors, head and neck surgeons may rely on systematic reviews such as the present analysis to guide management. |
format | Online Article Text |
id | pubmed-8549472 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | SAGE Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-85494722021-10-28 Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review Rehman, Rafey Dekhou, Antonio Osto, Muhammad Agemy, Jacob Chaaban, Amneah Yuhan, Brian Thorpe, Eric OTO Open Systematic Review/Meta-analysis OBJECTIVE: Aneurysmal bone cysts (ABCs) are blood-filled, locally destructive, benign bone tumors. Our objective was to conduct a systematic review outlining patient demographics, clinical characteristics, management, and outcomes of those with ABCs of the craniofacial bones. DATA SOURCES: Using PubMed, Cochrane, and Embase databases, 116 studies were included. REVIEW METHODS: Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, a systematic review was conducted. Data including patient demographics, clinical characteristics, treatment strategies, and patient outcomes were collected. RESULTS: A total of 127 patients from 116 studies were identified. Age ranged from 8 months to 90 years, with a mean age of 19.0 years. The most commonly affected craniofacial locations were the mandible (n = 31, 24.4%), temporal bone (n = 21, 16.5%), and occipital bone (n = 14, 11.0%). The most common presenting symptoms included a nontender mass (n = 51, 40.2%), a tender mass (n = 31, 24.4%), and generalized headache (n = 30, 23.6%). Imaging modalities included computed tomography (CT) and magnetic resonance imaging (MRI) (n = 77, 60.6%), CT alone (n = 31, 24.4%), and MRI alone (n = 8, 6.2%). All patients underwent surgical resection, with 1 patient requiring adjuvant radiation in addition to surgery. In total, 121 patients were disease-free and symptom-free without evidence of recurrence (17.4-month mean follow-up, 5.4 months average time to first recurrence). CONCLUSION: The current literature’s characterization of ABCs in craniofacial bones is limited to case reports and case series. Given the rarity of these tumors, head and neck surgeons may rely on systematic reviews such as the present analysis to guide management. SAGE Publications 2021-10-24 /pmc/articles/PMC8549472/ /pubmed/34723050 http://dx.doi.org/10.1177/2473974X211052950 Text en © The Authors 2021 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage). |
spellingShingle | Systematic Review/Meta-analysis Rehman, Rafey Dekhou, Antonio Osto, Muhammad Agemy, Jacob Chaaban, Amneah Yuhan, Brian Thorpe, Eric Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review |
title | Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review |
title_full | Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review |
title_fullStr | Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review |
title_full_unstemmed | Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review |
title_short | Aneurysmal Bone Cysts of the Craniofacial Origin: A Systematic Review |
title_sort | aneurysmal bone cysts of the craniofacial origin: a systematic review |
topic | Systematic Review/Meta-analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549472/ https://www.ncbi.nlm.nih.gov/pubmed/34723050 http://dx.doi.org/10.1177/2473974X211052950 |
work_keys_str_mv | AT rehmanrafey aneurysmalbonecystsofthecraniofacialoriginasystematicreview AT dekhouantonio aneurysmalbonecystsofthecraniofacialoriginasystematicreview AT ostomuhammad aneurysmalbonecystsofthecraniofacialoriginasystematicreview AT agemyjacob aneurysmalbonecystsofthecraniofacialoriginasystematicreview AT chaabanamneah aneurysmalbonecystsofthecraniofacialoriginasystematicreview AT yuhanbrian aneurysmalbonecystsofthecraniofacialoriginasystematicreview AT thorpeeric aneurysmalbonecystsofthecraniofacialoriginasystematicreview |