The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations

Introduction: Investigating variation in genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic (PGx) relationships. ADME gene variation is relatively well characterized in European and Asian populations, but data from Afri...

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Detalles Bibliográficos
Autores principales: da Rocha, Jorge E. B., Othman, Houcemeddine, Botha, Gerrit, Cottino, Laura, Twesigomwe, David, Ahmed, Samah, Drögemöller, Britt I., Fadlelmola, Faisal M., Machanick, Philip, Mbiyavanga, Mamana, Panji, Sumir, Wright, Galen E. B., Adebamowo, Clement, Matshaba, Mogomotsi, Ramsay, Michéle, Simo, Gustave, Simuunza, Martin C., Tiemessen, Caroline T., Baldwin, Sandra, Chiano, Mathias, Cox, Charles, Gross, Annette S., Thomas, Pamela, Gamo, Francisco-Javier, Hazelhurst, Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549571/
https://www.ncbi.nlm.nih.gov/pubmed/34721006
http://dx.doi.org/10.3389/fphar.2021.634016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549571/
https://www.ncbi.nlm.nih.gov/pubmed/34721006
http://dx.doi.org/10.3389/fphar.2021.634016

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