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The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations
Introduction: Investigating variation in genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic (PGx) relationships. ADME gene variation is relatively well characterized in European and Asian populations, but data from Afri...
Autores principales: | da Rocha, Jorge E. B., Othman, Houcemeddine, Botha, Gerrit, Cottino, Laura, Twesigomwe, David, Ahmed, Samah, Drögemöller, Britt I., Fadlelmola, Faisal M., Machanick, Philip, Mbiyavanga, Mamana, Panji, Sumir, Wright, Galen E. B., Adebamowo, Clement, Matshaba, Mogomotsi, Ramsay, Michéle, Simo, Gustave, Simuunza, Martin C., Tiemessen, Caroline T., Baldwin, Sandra, Chiano, Mathias, Cox, Charles, Gross, Annette S., Thomas, Pamela, Gamo, Francisco-Javier, Hazelhurst, Scott |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549571/ https://www.ncbi.nlm.nih.gov/pubmed/34721006 http://dx.doi.org/10.3389/fphar.2021.634016 |
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