Sequencing Directly from Clinical Specimens Reveals Genetic Variations in HCMV-Encoded Chemokine Receptor US28 That May Influence Antibody Levels and Interactions with Human Chemokines

Human cytomegalovirus (HCMV) is a beta-herpesvirus carried by ∼80% of the world’s population. Acute infections are asymptomatic in healthy individuals but generate diverse syndromes in neonates, solid organ transplant recipients, and HIV-infected individuals. The HCMV gene US28 encodes a homolog of...

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Detalles Bibliográficos
Autores principales: Waters, Shelley, Agostino, Mark, Lee, Silvia, Ariyanto, Ibnu, Kresoje, Nina, Leary, Shay, Munyard, Kylie, Gaudieri, Silvana, Gaff, Jessica, Irish, Ashley, Keil, Anthony D., Price, Patricia, Allcock, Richard J. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8549752/
https://www.ncbi.nlm.nih.gov/pubmed/34704798
http://dx.doi.org/10.1128/Spectrum.00020-21

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