An Osmotic Laxative Renders Mice Susceptible to Prolonged Clostridioides difficile Colonization and Hinders Clearance

Antibiotics are a major risk factor for Clostridioides difficile infections (CDIs) because of their impact on the microbiota. However, nonantibiotic medications such as the ubiquitous osmotic laxative polyethylene glycol 3350 (PEG 3350) also alter the microbiota. Clinicians also hypothesize that PEG...

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Detalles Bibliográficos
Autores principales: Tomkovich, Sarah, Taylor, Ana, King, Jacob, Colovas, Joanna, Bishop, Lucas, McBride, Kathryn, Royzenblat, Sonya, Lesniak, Nicholas A., Bergin, Ingrid L., Schloss, Patrick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550136/
https://www.ncbi.nlm.nih.gov/pubmed/34585964
http://dx.doi.org/10.1128/mSphere.00629-21

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