A previously uncharacterized two-component signaling system in uropathogenic Escherichia coli coordinates protection against host-derived oxidative stress with activation of hemolysin-mediated host cell pyroptosis

Uropathogenic Escherichia coli (UPEC) deploy an array of virulence factors to successfully establish urinary tract infections. Hemolysin is a pore-forming toxin, and its expression correlates with the severity of UPEC infection. Two-component signaling systems (TCSs) are a major mechanism by which b...

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Detalles Bibliográficos
Autores principales: Gu, Hongwei, Cai, Xuwang, Zhang, Xinyang, Luo, Jie, Zhang, Xiaoyang, Hu, Xiao, Cai, Wentong, Li, Ganwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550376/
https://www.ncbi.nlm.nih.gov/pubmed/34653218
http://dx.doi.org/10.1371/journal.ppat.1010005

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