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UMP-CMP kinase 2 gene expression in macrophages is dependent on the IRF3-IFNAR signaling axis

Toll-like receptors (TLRs) are highly-conserved pattern recognition receptors that mediate innate immune responses to invading pathogens and endogenous danger signals released from damaged and dying cells. Activation of TLRs trigger downstream signaling cascades, that culminate in the activation of...

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Detalles Bibliográficos
Autores principales: Kim, Hera, Subbannayya, Yashwanth, Humphries, Fiachra, Skejsol, Astrid, Pinto, Sneha M., Giambelluca, Miriam, Espevik, Terje, Fitzgerald, Katherine A., Kandasamy, Richard K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550426/
https://www.ncbi.nlm.nih.gov/pubmed/34705862
http://dx.doi.org/10.1371/journal.pone.0258989