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Translation of curative therapy concepts with T cell and cytokine antibody combinations for type 1 diabetes reversal in the IDDM rat

ABSTRACT: Proinflammatory cytokines released from the pancreatic islet immune cell infiltrate in type 1 diabetes (T1D) cause insulinopenia as a result of severe beta cell loss due to apoptosis. Diabetes prevention strategies targeting different cytokines with antibodies in combination with a T cell...

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Detalles Bibliográficos
Autores principales:	Jörns, Anne, Arndt, Tanja, Yamada, Shinichiro, Ishikawa, Daichi, Yoshimoto, Toshiaki, Terbish, Taivankhuu, Wedekind, Dirk, van der Meide, Peter H., Lenzen, Sigurd
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550584/ https://www.ncbi.nlm.nih.gov/pubmed/32607871 http://dx.doi.org/10.1007/s00109-020-01941-8

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