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Collagen polarization promotes epithelial elongation by stimulating locoregional cell proliferation

Epithelial networks are commonly generated by processes where multicellular aggregates elongate and branch. Here, we focus on understanding cellular mechanisms for elongation using an organotypic culture system as a model of mammary epithelial anlage. Isotropic cell aggregates broke symmetry and slo...

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Detalles Bibliográficos
Autores principales: Katsuno-Kambe, Hiroko, Teo, Jessica L, Ju, Robert J, Hudson, James, Stehbens, Samantha J, Yap, Alpha S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550756/
https://www.ncbi.nlm.nih.gov/pubmed/34661524
http://dx.doi.org/10.7554/eLife.67915