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Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2

Of the eight distinct polyubiquitin (polyUb) linkages that can be assembled, the roles of K48-linked polyUb (K48-polyUb) are the most established, with K48-polyUb modified proteins being targeted for degradation. MINDY1 and MINDY2 are members of the MINDY family of deubiquitinases (DUBs) that have e...

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Detalles Bibliográficos
Autores principales:	Abdul Rehman, Syed Arif, Armstrong, Lee A., Lange, Sven M., Kristariyanto, Yosua Adi, Gräwert, Tobias W., Knebel, Axel, Svergun, Dmitri I., Kulathu, Yogesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550791/ https://www.ncbi.nlm.nih.gov/pubmed/34529927 http://dx.doi.org/10.1016/j.molcel.2021.08.024

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