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Recent Advances in Functional Carbon Quantum Dots for Antitumour
Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in bio...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550800/ https://www.ncbi.nlm.nih.gov/pubmed/34720582 http://dx.doi.org/10.2147/IJN.S334012 |
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author | Cai, Rong Xiao, Long Liu, Meixiu Du, Fengyi Wang, Zhirong |
author_facet | Cai, Rong Xiao, Long Liu, Meixiu Du, Fengyi Wang, Zhirong |
author_sort | Cai, Rong |
collection | PubMed |
description | Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by “top-down” and “bottom-up” methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours. |
format | Online Article Text |
id | pubmed-8550800 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-85508002021-10-29 Recent Advances in Functional Carbon Quantum Dots for Antitumour Cai, Rong Xiao, Long Liu, Meixiu Du, Fengyi Wang, Zhirong Int J Nanomedicine Review Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by “top-down” and “bottom-up” methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours. Dove 2021-10-23 /pmc/articles/PMC8550800/ /pubmed/34720582 http://dx.doi.org/10.2147/IJN.S334012 Text en © 2021 Cai et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Review Cai, Rong Xiao, Long Liu, Meixiu Du, Fengyi Wang, Zhirong Recent Advances in Functional Carbon Quantum Dots for Antitumour |
title | Recent Advances in Functional Carbon Quantum Dots for Antitumour |
title_full | Recent Advances in Functional Carbon Quantum Dots for Antitumour |
title_fullStr | Recent Advances in Functional Carbon Quantum Dots for Antitumour |
title_full_unstemmed | Recent Advances in Functional Carbon Quantum Dots for Antitumour |
title_short | Recent Advances in Functional Carbon Quantum Dots for Antitumour |
title_sort | recent advances in functional carbon quantum dots for antitumour |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550800/ https://www.ncbi.nlm.nih.gov/pubmed/34720582 http://dx.doi.org/10.2147/IJN.S334012 |
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