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Recent Advances in Functional Carbon Quantum Dots for Antitumour

Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in bio...

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Detalles Bibliográficos
Autores principales: Cai, Rong, Xiao, Long, Liu, Meixiu, Du, Fengyi, Wang, Zhirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550800/
https://www.ncbi.nlm.nih.gov/pubmed/34720582
http://dx.doi.org/10.2147/IJN.S334012
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author Cai, Rong
Xiao, Long
Liu, Meixiu
Du, Fengyi
Wang, Zhirong
author_facet Cai, Rong
Xiao, Long
Liu, Meixiu
Du, Fengyi
Wang, Zhirong
author_sort Cai, Rong
collection PubMed
description Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by “top-down” and “bottom-up” methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours.
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spelling pubmed-85508002021-10-29 Recent Advances in Functional Carbon Quantum Dots for Antitumour Cai, Rong Xiao, Long Liu, Meixiu Du, Fengyi Wang, Zhirong Int J Nanomedicine Review Carbon quantum dots (CQDs) are an emerging class of quasi-zero-dimensional photoluminescent nanomaterials with particle sizes less than 10 nm. Owing to their favourable water dispersion, strong chemical inertia, stable optical performance, and good biocompatibility, CQDs have become prominent in biomedical fields. CQDs can be fabricated by “top-down” and “bottom-up” methods, both of which involve oxidation, carbonization, pyrolysis and polymerization. The functions of CQDs include biological imaging, biosensing, drug delivery, gene carrying, antimicrobial performance, photothermal ablation and so on, which enable them to be utilized in antitumour applications. The purpose of this review is to summarize the research progress of CQDs in antitumour applications from preparation and characterization to application prospects. Furthermore, the challenges and opportunities of CQDs are discussed along with future perspectives for precise individual therapy of tumours. Dove 2021-10-23 /pmc/articles/PMC8550800/ /pubmed/34720582 http://dx.doi.org/10.2147/IJN.S334012 Text en © 2021 Cai et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Cai, Rong
Xiao, Long
Liu, Meixiu
Du, Fengyi
Wang, Zhirong
Recent Advances in Functional Carbon Quantum Dots for Antitumour
title Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_full Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_fullStr Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_full_unstemmed Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_short Recent Advances in Functional Carbon Quantum Dots for Antitumour
title_sort recent advances in functional carbon quantum dots for antitumour
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550800/
https://www.ncbi.nlm.nih.gov/pubmed/34720582
http://dx.doi.org/10.2147/IJN.S334012
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