Cargando…

Total Saponin of Dioscorea collettii Attenuates MSU Crystal-Induced Inflammation by Inhibiting the Activation of the TLR4/NF-κB Signaling Pathway

BACKGROUND: Rhizomes from Dioscorea collettii are extensively used in traditional medicine for the treatment of arthritic diseases, particularly gouty arthritis (GA). This study aims to investigate whether the total saponin of Dioscorea collettii (TSD) can attenuate monosodium urate (MSU) crystal-in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guoying, Li, Li, Li, Siyue, Yang, Lei, Lv, Guangliang, Chen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550844/ https://www.ncbi.nlm.nih.gov/pubmed/34721647 http://dx.doi.org/10.1155/2021/8728473

Ejemplares similares

Total saponin of Dioscorea collettii attenuates MSU crystal-induced inflammation via inhibiting the activation of the NALP3 inflammasome and caspase-1 in THP-1 macrophages
por: Wang, Lu, et al.
Publicado: (2020)

Dihydroisocoumarins and Dihydroisoflavones from the Rhizomes of Dioscorea collettii with Cytotoxic Activity and Structural Revision of 2,2′-Oxybis(1,4-di-tert-butylbenzene)
por: Jing, Songsong, et al.
Publicado: (2021)

Therapeutic Effect of Total Saponins from Dioscorea nipponica Makino on Gouty Arthritis Based on the NF-κB Signal Pathway: An In vitro Study
por: Zhou, Qi, et al.
Publicado: (2016)

Curcumin attenuates MSU crystal-induced inflammation by inhibiting the degradation of IκBα and blocking mitochondrial damage
por: Chen, Baofeng, et al.
Publicado: (2019)

Total saponin of Dioscoreae hypoglaucae rhizoma ameliorates streptozotocin-induced diabetic nephropathy
por: Guo, Changrun, et al.
Publicado: (2016)

The genome of Dioscorea zingiberensis sheds light on the biosynthesis, origin and evolution of the medicinally important diosgenin saponins
por: Li, Yi, et al.
Publicado: (2022)

Evaluation of different pretreatments on microbial transformation of saponins in Dioscorea zingiberensis for diosgenin production
por: Zheng, Tianxiang, et al.
Publicado: (2014)

Targeting Tristetraprolin Expression or Functional Activity Regulates Inflammatory Response Induced by MSU Crystals
por: lv, Linxi, et al.
Publicado: (2021)

Palmatine Protects Against MSU-Induced Gouty Arthritis via Regulating the NF-κB/NLRP3 and Nrf2 Pathways
por: Cheng, Juan-Juan, et al.
Publicado: (2022)

Phycocyanin attenuates pulmonary fibrosis via the TLR2-MyD88-NF-κB signaling pathway
por: Li, Chengcheng, et al.
Publicado: (2017)

β-Caryophyllene Ameliorates MSU-Induced Gouty Arthritis and Inflammation Through Inhibiting NLRP3 and NF-κB Signal Pathway: In Silico and In Vivo
por: Li, Wan-Yang, et al.
Publicado: (2021)

Study of Saponin Components after Biotransformation of Dioscorea nipponica by Endophytic Fungi C39
por: Huang, Nannan, et al.
Publicado: (2022)

OR6-004 – MRP8/14 promote MSU-crystal induced inflammation
por: Holzinger, D, et al.
Publicado: (2013)

Gynostemma pentaphyllum saponins attenuate inflammation in vitro and in vivo by inhibition of NF-κB and STAT3 signaling
por: Wong, Wing-Yan, et al.
Publicado: (2017)

Anti-inflammation effects of the total saponin fraction from Dioscorea nipponica Makino on rats with gouty arthritis by influencing MAPK signalling pathway
por: Zhou, Qi, et al.
Publicado: (2020)

Ginseng Saponin Rb1 Attenuates Cigarette Smoke Exposure-Induced Inflammation, Apoptosis and Oxidative Stress via Activating Nrf2 and Inhibiting NF-κB Signaling Pathways
por: Li, Zhizheng, et al.
Publicado: (2023)

Isoflurane Preconditioning Attenuates Brain Injury Induced by Electromagnetic Pulse via the TLR4/NFκB Signaling Pathway
por: Li, Jiang-Jing, et al.
Publicado: (2019)

Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma
por: Yang, Gui-Ya, et al.
Publicado: (2021)

Maresin1 ameliorates MSU crystal-induced inflammation by upregulating Prdx5 expression
por: Jiang, Hui, et al.
Publicado: (2023)

MSU contends for role in the future of physics
por: Martin, M
Publicado: (2002)

Central-Region Studies for the MSU Cyclotron
por: Blosser, H G, et al.
Publicado: (1963)

Radio-Frequency System for the MSU Cyclotron
por: Johnson, W P
Publicado: (1963)

MSU girl is a viral sensation
Publicado: (2008)

Naringenin attenuates inflammation and apoptosis of osteoarthritic chondrocytes via the TLR4/TRAF6/NF-κB pathway
por: Wang, Yan, et al.
Publicado: (2023)

NF-κB inhibition attenuates LPS-induced TLR4 activation in monocyte cells
por: Wan, Jian, et al.
Publicado: (2016)

Berberine attenuates septic cardiomyopathy by inhibiting TLR4/NF-κB signalling in rats
por: Chen, Huiqi, et al.
Publicado: (2021)

P2X7R Mediates the Synergistic Effect of ATP and MSU Crystals to Induce Acute Gouty Arthritis
por: Li, Xiaoling, et al.
Publicado: (2023)

Factors influencing the kinetics of MSU crystal depletion measured with dual-energy CT in patients with gout
por: Laurent, Victor, et al.
Publicado: (2023)

The protective effects of S14G-humanin (HNG) against mono-sodium urate (MSU) crystals- induced gouty arthritis
por: Zhang, Jihui, et al.
Publicado: (2021)

Experimental Facilities and Resolution Capability of the MSU Cyclotron
por: Blosser, H G, et al.
Publicado: (1963)

Orbit Calculations on the Extraction System for the MSU Cyclotron
por: Gordon, M M, et al.
Publicado: (1963)

Pycnogenol attenuates atherosclerosis by regulating lipid metabolism through the TLR4–NF-κB pathway
por: Luo, Hong, et al.
Publicado: (2015)

Antifungal Effects of Saponin Extract from Rhizomes of Dioscorea panthaica Prain et Burk against Candida albicans
por: Yang, Longfei, et al.
Publicado: (2018)

Steroidal Saponins Isolated from the Rhizome of Dioscorea tokoro Inhibit Cell Growth and Autophagy in Hepatocellular Carcinoma Cells
por: Okubo, Shinya, et al.
Publicado: (2021)

Lipoxin A4 attenuates MSU-crystal-induced NLRP3 inflammasome activation through suppressing Nrf2 thereby increasing TXNRD2
por: Zhou, You, et al.
Publicado: (2022)

Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway
por: Hu, Jian, et al.
Publicado: (2022)

Metformin Attenuates Ischemia-reperfusion Injury of Fatty Liver in Rats Through Inhibition of the TLR4/NF-κB Axis
por: Li, Xiaohua, et al.
Publicado: (2020)

Exercise Training Attenuates Hypertension Through TLR4/MyD88/NF-κB Signaling in the Hypothalamic Paraventricular Nucleus
por: Qi, Jie, et al.
Publicado: (2019)

MicroRNA-146 attenuates lipopolysaccharide induced ovarian dysfunction by inhibiting the TLR4/NF- κB signaling pathway
por: He, Fengping, et al.
Publicado: (2022)

Saponin 1 Induces Apoptosis and Suppresses NF-κB-Mediated Survival Signaling in Glioblastoma Multiforme (GBM)
por: Li, Juan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pr6vm9vr7oir8vvs3ih8p5n9aa