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A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021

INTRODUCTION: Depression is the most common mental health problem in people living with the human immune virus. It ranges from 11% to 63% in low- and middle-income countries. Depression was high in people living with HIV/AIDS in developing countries, especially in the Ethiopian context. Even though...

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Autores principales: Zewudie, Bitew Tefera, Geze, Shegaw, Mesfin, Yibeltal, Argaw, Muche, Abebe, Haimanot, Mekonnen, Zebene, Tesfa, Shegaw, Chekole, Bogale, Tadesse, Betelhem, Aynalem, Agere, Lankrew, Tadele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550854/
https://www.ncbi.nlm.nih.gov/pubmed/34721902
http://dx.doi.org/10.1155/2021/8545934
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author Zewudie, Bitew Tefera
Geze, Shegaw
Mesfin, Yibeltal
Argaw, Muche
Abebe, Haimanot
Mekonnen, Zebene
Tesfa, Shegaw
Chekole, Bogale
Tadesse, Betelhem
Aynalem, Agere
Lankrew, Tadele
author_facet Zewudie, Bitew Tefera
Geze, Shegaw
Mesfin, Yibeltal
Argaw, Muche
Abebe, Haimanot
Mekonnen, Zebene
Tesfa, Shegaw
Chekole, Bogale
Tadesse, Betelhem
Aynalem, Agere
Lankrew, Tadele
author_sort Zewudie, Bitew Tefera
collection PubMed
description INTRODUCTION: Depression is the most common mental health problem in people living with the human immune virus. It ranges from 11% to 63% in low- and middle-income countries. Depression was high in people living with HIV/AIDS in developing countries, especially in the Ethiopian context. Even though depression has negative consequences on HIV-positive patients, the care given for depression in resource-limited countries like Ethiopia is below the standard in their HIV care programs. METHOD: International databases (Google Scholar, PubMed, Hinari, Embase, and Scopus) and Ethiopian university repository online have been covered in this review. Data were extracted using Microsoft Excel and analyzed by using the Stata version 14 software program. We detected the heterogeneity between studies using the I(2) test. We checked publication bias using a funnel plot test. RESULTS: The overall pooled depression prevalence among adult HIV/AIDS patients attending antiretroviral therapy in Ethiopia was 36.3% (95% CI: 28.4%, 44.2%) based on the random effect analysis. Adult HIV/AIDS patients having CD4count < 200(AOR = 5.1; 95% CI: 2.89, 8.99), widowed marital status (AOR = 3.7; 95% CI: 2.394, 5.789), medication nonadherence (AOR = 2.3; 95% CI: 1.63, 3.15), poor social support (2.986) (95% CI: 2.139, 4.169), perceived social stigma (2.938) (2.305, 3.743), opportunistic infections (3.010) (2.182, 4.151), and adverse drug reactions (4.013) (1.971, 8.167) were significantly associated with depression among adult HIV/AIDS patients on antiretroviral therapy, in Ethiopia. Conclusion and Recommendation. The pooled depression prevalence among adult HIV/AIDS patients attending antiretroviral therapy in Ethiopia was higher than the general population and is alarming for the government to take special consideration for HIV-positive patients. Depression assessment for all HIV-positive patients and integrating with mental health should be incorporated to ensure early detection, prevention, and treatment. Community-based and longitudinal study designs mainly focusing on the incidence and determinants of depression among adult HIV/AIDS patients should be done in the future.
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spelling pubmed-85508542021-10-28 A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021 Zewudie, Bitew Tefera Geze, Shegaw Mesfin, Yibeltal Argaw, Muche Abebe, Haimanot Mekonnen, Zebene Tesfa, Shegaw Chekole, Bogale Tadesse, Betelhem Aynalem, Agere Lankrew, Tadele Depress Res Treat Review Article INTRODUCTION: Depression is the most common mental health problem in people living with the human immune virus. It ranges from 11% to 63% in low- and middle-income countries. Depression was high in people living with HIV/AIDS in developing countries, especially in the Ethiopian context. Even though depression has negative consequences on HIV-positive patients, the care given for depression in resource-limited countries like Ethiopia is below the standard in their HIV care programs. METHOD: International databases (Google Scholar, PubMed, Hinari, Embase, and Scopus) and Ethiopian university repository online have been covered in this review. Data were extracted using Microsoft Excel and analyzed by using the Stata version 14 software program. We detected the heterogeneity between studies using the I(2) test. We checked publication bias using a funnel plot test. RESULTS: The overall pooled depression prevalence among adult HIV/AIDS patients attending antiretroviral therapy in Ethiopia was 36.3% (95% CI: 28.4%, 44.2%) based on the random effect analysis. Adult HIV/AIDS patients having CD4count < 200(AOR = 5.1; 95% CI: 2.89, 8.99), widowed marital status (AOR = 3.7; 95% CI: 2.394, 5.789), medication nonadherence (AOR = 2.3; 95% CI: 1.63, 3.15), poor social support (2.986) (95% CI: 2.139, 4.169), perceived social stigma (2.938) (2.305, 3.743), opportunistic infections (3.010) (2.182, 4.151), and adverse drug reactions (4.013) (1.971, 8.167) were significantly associated with depression among adult HIV/AIDS patients on antiretroviral therapy, in Ethiopia. Conclusion and Recommendation. The pooled depression prevalence among adult HIV/AIDS patients attending antiretroviral therapy in Ethiopia was higher than the general population and is alarming for the government to take special consideration for HIV-positive patients. Depression assessment for all HIV-positive patients and integrating with mental health should be incorporated to ensure early detection, prevention, and treatment. Community-based and longitudinal study designs mainly focusing on the incidence and determinants of depression among adult HIV/AIDS patients should be done in the future. Hindawi 2021-10-20 /pmc/articles/PMC8550854/ /pubmed/34721902 http://dx.doi.org/10.1155/2021/8545934 Text en Copyright © 2021 Bitew Tefera Zewudie et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Zewudie, Bitew Tefera
Geze, Shegaw
Mesfin, Yibeltal
Argaw, Muche
Abebe, Haimanot
Mekonnen, Zebene
Tesfa, Shegaw
Chekole, Bogale
Tadesse, Betelhem
Aynalem, Agere
Lankrew, Tadele
A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021
title A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021
title_full A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021
title_fullStr A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021
title_full_unstemmed A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021
title_short A Systematic Review and Meta-Analysis on Depression and Associated Factors among Adult HIV/AIDS-Positive Patients Attending ART Clinics of Ethiopia: 2021
title_sort systematic review and meta-analysis on depression and associated factors among adult hiv/aids-positive patients attending art clinics of ethiopia: 2021
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550854/
https://www.ncbi.nlm.nih.gov/pubmed/34721902
http://dx.doi.org/10.1155/2021/8545934
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