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Therapeutic mTOR blockade in systemic autoimmunity: Implications for antiviral immunity and extension of lifespan
The mechanistic target of rapamycin (mTOR) pathway integrates metabolic cues into cell fate decisions. A particularly fateful event during the adaptive immune response is the engagement of a T cell receptor by its cognate antigen presented by an antigen-presenting cell (APC). Here, the induction of...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier B.V.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550885/ https://www.ncbi.nlm.nih.gov/pubmed/34718162 http://dx.doi.org/10.1016/j.autrev.2021.102984 |