Myeloid-derived suppressor cell subtypes differentially influence T-cell function, T-helper subset differentiation, and clinical course in CLL

Cancer pathogenesis involves the interplay of tumor- and microenvironment-derived stimuli. Here we focused on the influence of an immunomodulatory cell type, myeloid-derived suppressor cells (MDSCs), and their lineage-related subtypes on autologous T lymphocytes. Although MDSCs as a group correlated...

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Detalles Bibliográficos
Autores principales: Ferrer, Gerardo, Jung, Byeongho, Chiu, Pui Yan, Aslam, Rukhsana, Palacios, Florencia, Mazzarello, Andrea Nicola, Vergani, Stefano, Bagnara, Davide, Chen, Shih-Shih, Yancopoulos, Sophia, Xochelli, Aliki, Yan, Xiao-Jie, Burger, Jan A., Barrientos, Jacqueline C., Kolitz, Jonathan E., Allen, Steven L., Stamatopoulos, Kostas, Rai, Kanti R., Sherry, Barbara, Chiorazzi, Nicholas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550941/
https://www.ncbi.nlm.nih.gov/pubmed/33935280
http://dx.doi.org/10.1038/s41375-021-01249-7

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