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An epigenetic predictor of death captures multi-modal measures of brain health

Individuals of the same chronological age exhibit disparate rates of biological ageing. Consequently, a number of methodologies have been proposed to determine biological age and primarily exploit variation at the level of DNA methylation (DNAm). A novel epigenetic clock, termed ‘DNAm GrimAge’ has o...

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Detalles Bibliográficos
Autores principales:	Hillary, Robert F., Stevenson, Anna J., Cox, Simon R., McCartney, Daniel L., Harris, Sarah E., Seeboth, Anne, Higham, Jon, Sproul, Duncan, Taylor, Adele M., Redmond, Paul, Corley, Janie, Pattie, Alison, Hernández, Maria del. C. Valdés, Muñoz-Maniega, Susana, Bastin, Mark E., Wardlaw, Joanna M., Horvath, Steve, Ritchie, Craig W., Spires-Jones, Tara L., McIntosh, Andrew M., Evans, Kathryn L., Deary, Ian J., Marioni, Riccardo E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550950/ https://www.ncbi.nlm.nih.gov/pubmed/31796892 http://dx.doi.org/10.1038/s41380-019-0616-9

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