Leptin regulates exon-specific transcription of the Bdnf gene via epigenetic modifications mediated by an AKT/p300 HAT cascade

Leptin is an adipocyte-derived hormone with pleiotropic functions affecting appetite and mood. While leptin’s role in the regulation of appetite has been extensively studied in hypothalamic neurons, its function in the hippocampus, where it regulates mood-related behaviors, is poorly understood. Her...

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Detalles Bibliográficos
Autores principales: Li, Chen, Meng, Fantao, Lei, Yun, Liu, Jing, Zhang, Jingyan, Liu, Fang, Liu, Cuilan, Guo, Ming, Lu, Xin-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550971/
https://www.ncbi.nlm.nih.gov/pubmed/33106599
http://dx.doi.org/10.1038/s41380-020-00922-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550971/
https://www.ncbi.nlm.nih.gov/pubmed/33106599
http://dx.doi.org/10.1038/s41380-020-00922-0

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