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Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis

Low reproducibility in gene expression profiles has been observed in transcriptome studies, and this often limits applying findings to clinical practice. Here, we show time-of-day effects on gene expression and analytical schemes to increase the reproducibility in expression patterns. We recruited p...

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Detalles Bibliográficos
Autores principales: Huang, Suihong, Wu, Tan, Lau, Alexander Y., Au, Cheryl, Huang, Hao, Wang, Xin, Kim, Jin Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551071/
https://www.ncbi.nlm.nih.gov/pubmed/34746708
http://dx.doi.org/10.1016/j.isci.2021.103247