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Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis
Low reproducibility in gene expression profiles has been observed in transcriptome studies, and this often limits applying findings to clinical practice. Here, we show time-of-day effects on gene expression and analytical schemes to increase the reproducibility in expression patterns. We recruited p...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551071/ https://www.ncbi.nlm.nih.gov/pubmed/34746708 http://dx.doi.org/10.1016/j.isci.2021.103247 |