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Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic Compounds

Dihydroceramide desaturase (Degs1) catalyses the introduction of a 4,5-trans double bond into dihydroceramide to form ceramide. We show here that Degs1 is polyubiquitinated in response to retinol derivatives, phenolic compounds or anti-oxidants in HEK293T cells. The functional predominance of native...

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Detalles Bibliográficos
Autores principales:	Alsanafi, Mariam, Brown, Ryan D. R., Oh, Jeongah, Adams, David R., Torta, Federico, Pyne, Nigel J., Pyne, Susan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Original Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551130/ https://www.ncbi.nlm.nih.gov/pubmed/33991313 http://dx.doi.org/10.1007/s12013-021-00990-1

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