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Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma

Multiple myeloma (MM) is a devastating disease with low survival rates worldwide. The mean lifetime of patients may be extendable with new drug alternatives. Aurora A kinase (AURKA) is crucial in oncogenesis, because its overexpression or amplification may incline the development of various types of...

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Detalles Bibliográficos
Autores principales:	Özenver, Nadire, Abdelfatah, Sara, Klinger, Anette, Fleischer, Edmond, Efferth, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2020
Materias:	Preclinical Studies
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551148/ https://www.ncbi.nlm.nih.gov/pubmed/32978717 http://dx.doi.org/10.1007/s10637-020-01012-2

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