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RBM15 promotes hepatocellular carcinoma progression by regulating N6-methyladenosine modification of YES1 mRNA in an IGF2BP1-dependent manner

The function of the N6-methyladenosine (m(6)A) methyltransferase RNA-binding motif protein 15 (RBM15) in hepatocellular carcinoma (HCC) has not been thoroughly investigated. Here we determined the clinical value, biological functions, and potential mechanisms of RBM15 in HCC. Expression of RBM15 was...

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Detalles Bibliográficos
Autores principales: Cai, Xianlei, Chen, Yunhao, Man, Da, Yang, Beng, Feng, Xiaode, Zhang, Deguo, Chen, Junru, Wu, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551180/
https://www.ncbi.nlm.nih.gov/pubmed/34707107
http://dx.doi.org/10.1038/s41420-021-00703-w

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