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Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time

Ribosomal biogenesis has been studied by biochemical, genetic and electron microscopic approaches, but live cell data on the in vivo kinetics are still missing. Here we analyse the export kinetics of the large ribosomal subunit (pre-60S particle) through single NPCs in human cells. We established a...

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Detalles Bibliográficos
Autores principales:	Ruland, Jan Andreas, Krüger, Annika Marie, Dörner, Kerstin, Bhatia, Rohan, Wirths, Sabine, Poetes, Daniel, Kutay, Ulrike, Siebrasse, Jan Peter, Kubitscheck, Ulrich
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551241/ https://www.ncbi.nlm.nih.gov/pubmed/34707094 http://dx.doi.org/10.1038/s41467-021-26323-7

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