Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures

The utility of pathway signatures lies in their capability to determine whether a specific pathway or biological process is dysregulated in a given patient. These signatures have been widely used in machine learning (ML) methods for a variety of applications including precision medicine, drug repurp...

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Detalles Bibliográficos
Autores principales: Golriz Khatami, Sepehr, Mubeen, Sarah, Bharadhwaj, Vinay Srinivas, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin, Domingo-Fernández, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551267/
https://www.ncbi.nlm.nih.gov/pubmed/34707117
http://dx.doi.org/10.1038/s41540-021-00199-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551267/
https://www.ncbi.nlm.nih.gov/pubmed/34707117
http://dx.doi.org/10.1038/s41540-021-00199-1

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