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Using predictive machine learning models for drug response simulation by calibrating patient-specific pathway signatures
The utility of pathway signatures lies in their capability to determine whether a specific pathway or biological process is dysregulated in a given patient. These signatures have been widely used in machine learning (ML) methods for a variety of applications including precision medicine, drug repurp...
Autores principales: | Golriz Khatami, Sepehr, Mubeen, Sarah, Bharadhwaj, Vinay Srinivas, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin, Domingo-Fernández, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551267/ https://www.ncbi.nlm.nih.gov/pubmed/34707117 http://dx.doi.org/10.1038/s41540-021-00199-1 |
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