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Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients

Lymph nodes (LNs) and distant metastases can arise from independent subclones of the primary tumor. Herein, we characterized the molecular landscape and the differences between LNs, distant metastases and primary colorectal cancers (CRCs). Samples were analyzed using next generation sequencing (NGS,...

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Detalles Bibliográficos
Autores principales: Puccini, Alberto, Seeber, Andreas, Xiu, Joanne, Goldberg, Richard M., Soldato, Davide, Grothey, Axel, Shields, Anthony F., Salem, Mohamed E., Battaglin, Francesca, Berger, Martin D., El-Deiry, Wafik S., Tokunaga, Ryuma, Naseem, Madiha, Zhang, Wu, Arora, Sukeshi Patel, Khushman, Moh’d M., Hall, Michael J., Philip, Philip A., Marshall, John L., Korn, W. Michael, Lenz, Heinz-Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551277/
https://www.ncbi.nlm.nih.gov/pubmed/34707195
http://dx.doi.org/10.1038/s41698-021-00230-y