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RCAN1.4 attenuates renal fibrosis through inhibiting calcineurin-mediated nuclear translocation of NFAT2

Chronic kidney disease (CKD) is thus deemed to a global health problem. Renal fibrosis, characterized by accumulation of extracellular matrix (ECM) components in the kidney, is considered a common pathway leading to CKD. Regulator of calcineurin1 (RCAN1), identified as a competitive endogenous inhib...

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Detalles Bibliográficos
Autores principales: Zhang, Jianjian, Chen, Hui, Weng, Xiaodong, Liu, Hao, Chen, Zhiyuan, Huang, Qin, Wang, Lei, Liu, Xiuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551295/
https://www.ncbi.nlm.nih.gov/pubmed/34707090
http://dx.doi.org/10.1038/s41420-021-00713-8

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