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The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging

Pituitary homeobox 3 (Pitx3) is required for the terminal differentiation of nigrostriatal dopaminergic neurons during neuronal development. However, whether Pitx3 contributes to the normal physiological function and cell-type identity of adult neurons remains unknown. To explore the role of Pitx3 i...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Chen, Xi, Wang, Yuanyuan, Li, Song, Cai, Huaibin, Le, Weidong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551333/
https://www.ncbi.nlm.nih.gov/pubmed/34707106
http://dx.doi.org/10.1038/s41419-021-04319-x