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The essential role of transcription factor Pitx3 in preventing mesodiencephalic dopaminergic neurodegeneration and maintaining neuronal subtype identities during aging
Pituitary homeobox 3 (Pitx3) is required for the terminal differentiation of nigrostriatal dopaminergic neurons during neuronal development. However, whether Pitx3 contributes to the normal physiological function and cell-type identity of adult neurons remains unknown. To explore the role of Pitx3 i...
Autores principales: | Wang, Ying, Chen, Xi, Wang, Yuanyuan, Li, Song, Cai, Huaibin, Le, Weidong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551333/ https://www.ncbi.nlm.nih.gov/pubmed/34707106 http://dx.doi.org/10.1038/s41419-021-04319-x |
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