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DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells

DNA-dependent protein kinase catalytic subunit (DNA-PKcs) is known primarily for its function in DNA double-stranded break repair and nonhomologous end joining (NHEJ). However, DNA-PKcs also has a critical yet undefined role in immunity impacting both myeloid and lymphoid cell lineages spurring inte...

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Detalles Bibliográficos
Autores principales:	Waldrip, Zachary J., Burdine, Lyle, Harrison, David K., Azevedo-Pouly, Ana Clara, Storey, Aaron J., Moffett, Olivia G., Mackintosh, Samuel G., Burdine, Marie Schluterman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551498/ https://www.ncbi.nlm.nih.gov/pubmed/34562454 http://dx.doi.org/10.1016/j.jbc.2021.101209

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