CKB inhibits epithelial-mesenchymal transition and prostate cancer progression by sequestering and inhibiting AKT activation

Epithelial-mesenchymal transition (EMT) contributes to tumor invasion, metastasis and drug resistance. AKT activation is key in a number of cellular processes. While many positive regulators for either EMT or AKT activation have been reported, few negative regulators are established. Through kinase...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Hulsurkar, Mohit, Zhuo, Lijuan, Xu, Jinbang, Yang, Han, Naderinezhad, Samira, Wang, Lin, Zhang, Guoliang, Ai, Nanping, Li, Linna, Chang, Jeffrey T., Zhang, Songlin, Fazli, Ladan, Creighton, Chad J., Bai, Fang, Ittmann, Michael M., Gleave, Martin E., Li, Wenliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551525/
https://www.ncbi.nlm.nih.gov/pubmed/34706306
http://dx.doi.org/10.1016/j.neo.2021.09.005

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