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Omega-3 versus Omega-6 fatty acid availability is controlled by hydrophobic site geometries of phospholipase A(2)s
Human phospholipase A(2)s (PLA(2)) constitute a superfamily of enzymes that hydrolyze the sn-2 acyl-chain of glycerophospholipids, producing lysophospholipids and free fatty acids. Each PLA(2) enzyme type contributes to specific biological functions based on its expression, subcellular localization,...
Autores principales: | Hayashi, Daiki, Mouchlis, Varnavas D., Dennis, Edward A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551542/ https://www.ncbi.nlm.nih.gov/pubmed/34474084 http://dx.doi.org/10.1016/j.jlr.2021.100113 |
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