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Statin withdrawal and treating COVID‐19 patients
Most but not all observational studies of statin treatment of COVID‐19 patients suggest that treatment improves outcomes. However, almost all of these studies fail to consider that withdrawing statins after hospital admission may have detrimental effects, a finding which cardiovascular investigators...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551562/ https://www.ncbi.nlm.nih.gov/pubmed/34708573 http://dx.doi.org/10.1002/prp2.861 |
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author | Fedson, David S. |
author_facet | Fedson, David S. |
author_sort | Fedson, David S. |
collection | PubMed |
description | Most but not all observational studies of statin treatment of COVID‐19 patients suggest that treatment improves outcomes. However, almost all of these studies fail to consider that withdrawing statins after hospital admission may have detrimental effects, a finding which cardiovascular investigators have known for 15–20 years. Continuing or starting statin treatment after hospital admission consistently improves cardiovascular outcomes. Similarly, inpatient statin treatment of COVID‐19 improves survival. For this reason, observational studies of the effectiveness of outpatient‐documented statin treatment of COVID‐19 patients must consider the negative consequences of statin withdrawal after hospital admission. |
format | Online Article Text |
id | pubmed-8551562 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85515622021-11-04 Statin withdrawal and treating COVID‐19 patients Fedson, David S. Pharmacol Res Perspect Short Report Most but not all observational studies of statin treatment of COVID‐19 patients suggest that treatment improves outcomes. However, almost all of these studies fail to consider that withdrawing statins after hospital admission may have detrimental effects, a finding which cardiovascular investigators have known for 15–20 years. Continuing or starting statin treatment after hospital admission consistently improves cardiovascular outcomes. Similarly, inpatient statin treatment of COVID‐19 improves survival. For this reason, observational studies of the effectiveness of outpatient‐documented statin treatment of COVID‐19 patients must consider the negative consequences of statin withdrawal after hospital admission. John Wiley and Sons Inc. 2021-10-27 /pmc/articles/PMC8551562/ /pubmed/34708573 http://dx.doi.org/10.1002/prp2.861 Text en © 2021 The Authors. Pharmacology Research & Perspectives published by John Wiley & Sons Ltd, British Pharmacological Society and American Society for Pharmacology and Experimental Therapeutics. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Short Report Fedson, David S. Statin withdrawal and treating COVID‐19 patients |
title | Statin withdrawal and treating COVID‐19 patients |
title_full | Statin withdrawal and treating COVID‐19 patients |
title_fullStr | Statin withdrawal and treating COVID‐19 patients |
title_full_unstemmed | Statin withdrawal and treating COVID‐19 patients |
title_short | Statin withdrawal and treating COVID‐19 patients |
title_sort | statin withdrawal and treating covid‐19 patients |
topic | Short Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551562/ https://www.ncbi.nlm.nih.gov/pubmed/34708573 http://dx.doi.org/10.1002/prp2.861 |
work_keys_str_mv | AT fedsondavids statinwithdrawalandtreatingcovid19patients |