A bioorthogonal chemical reporter for fatty acid synthase–dependent protein acylation

Mammalian cells acquire fatty acids (FAs) from dietary sources or via de novo palmitate production by fatty acid synthase (FASN). Although most cells express FASN at low levels, it is upregulated in cancers of the breast, prostate, and liver, among others, and is required during the replication of m...

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Detalles Bibliográficos
Autores principales: Karthigeyan, Krithika P., Zhang, Lizhi, Loiselle, David R., Haystead, Timothy A.J., Bhat, Menakshi, Yount, Jacob S., Kwiek, Jesse J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551652/
https://www.ncbi.nlm.nih.gov/pubmed/34606827
http://dx.doi.org/10.1016/j.jbc.2021.101272

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