Three-dimensional organoid culture unveils resistance to clinical therapies in adult and pediatric glioblastoma

BACKGROUND: Glioblastoma (GBM) is the most common primary brain tumor with a dismal prognosis. The inherent cellular diversity and interactions within tumor microenvironments represent significant challenges to effective treatment. Traditional culture methods such as adherent or sphere cultures may...

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Detalles Bibliográficos
Autores principales: Sundar, Swetha J., Shakya, Sajina, Barnett, Austin, Wallace, Lisa C., Jeon, Hyemin, Sloan, Andrew, Recinos, Violette, Hubert, Christopher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551697/
https://www.ncbi.nlm.nih.gov/pubmed/34700192
http://dx.doi.org/10.1016/j.tranon.2021.101251

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