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The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump

In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable perip...

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Detalles Bibliográficos
Autores principales: Wu, Peng, Xiang, Wenjing, Yin, Chengke, Li, Shu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551725/
https://www.ncbi.nlm.nih.gov/pubmed/34721085
http://dx.doi.org/10.3389/fphys.2021.766867
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author Wu, Peng
Xiang, Wenjing
Yin, Chengke
Li, Shu
author_facet Wu, Peng
Xiang, Wenjing
Yin, Chengke
Li, Shu
author_sort Wu, Peng
collection PubMed
description In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable peripheral components, little attention has been paid to the portable and wearable performance of the blood pump itself. This study reported a novel design of a wearable and portable extracorporeal centrifugal blood pump. Based on an in-house centrifugal maglev blood pump, the wearable and portable blood pump was designed with parallel inlet and outlet pipes to improve the wearable performance. A ring cavity was set at the inlet to convert the circumferential velocity of the inlet pipe to an axial velocity. The hydraulic and hemolytic performance of the baseline and portable blood pumps were analyzed and compared. Compared with the baseline pump, the hydrodynamic and hemolytic performance of the portable pump has been maintained without serious degradation. The results of this study will improve the life quality of patients with heart failure, and enhance the clinical benefits of artificial heart.
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spelling pubmed-85517252021-10-29 The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump Wu, Peng Xiang, Wenjing Yin, Chengke Li, Shu Front Physiol Physiology In recent years, blood pumps have become the bridge to heart transplantation for patients with heart failure. Portability and wearability of blood pumps should be considered to ensure patient satisfaction in everyday life. To date, the focus has been on the development of portable and wearable peripheral components, little attention has been paid to the portable and wearable performance of the blood pump itself. This study reported a novel design of a wearable and portable extracorporeal centrifugal blood pump. Based on an in-house centrifugal maglev blood pump, the wearable and portable blood pump was designed with parallel inlet and outlet pipes to improve the wearable performance. A ring cavity was set at the inlet to convert the circumferential velocity of the inlet pipe to an axial velocity. The hydraulic and hemolytic performance of the baseline and portable blood pumps were analyzed and compared. Compared with the baseline pump, the hydrodynamic and hemolytic performance of the portable pump has been maintained without serious degradation. The results of this study will improve the life quality of patients with heart failure, and enhance the clinical benefits of artificial heart. Frontiers Media S.A. 2021-10-14 /pmc/articles/PMC8551725/ /pubmed/34721085 http://dx.doi.org/10.3389/fphys.2021.766867 Text en Copyright © 2021 Wu, Xiang, Yin and Li. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Physiology
Wu, Peng
Xiang, Wenjing
Yin, Chengke
Li, Shu
The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_full The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_fullStr The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_full_unstemmed The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_short The Design and Evaluation of a Portable Extracorporeal Centrifugal Blood Pump
title_sort design and evaluation of a portable extracorporeal centrifugal blood pump
topic Physiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551725/
https://www.ncbi.nlm.nih.gov/pubmed/34721085
http://dx.doi.org/10.3389/fphys.2021.766867
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