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Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling

Podophyllotoxin (PT), a lignan compound from the roots and rhizomes of Podophyllum peltatum, has diverse pharmacological activities including anticancer effect in several types of cancer. The molecular mechanism of the anticancer effects of PT on colorectal cancer cells has not been reported yet. In...

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Detalles Bibliográficos
Autores principales:	Lee, Seung-On, Joo, Sang Hoon, Kwak, Ah-Won, Lee, Mee-Hyun, Seo, Ji-Hye, Cho, Seung-Sik, Yoon, Goo, Chae, Jung-Il, Shim, Jung-Hyun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Korean Society of Applied Pharmacology 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551740/ https://www.ncbi.nlm.nih.gov/pubmed/34642263 http://dx.doi.org/10.4062/biomolther.2021.143

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