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SARS CoV-2 seroprevalence in a US school district during COVID-19

Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in...

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Detalles Bibliográficos
Autores principales: Bullis, Sean S M, Grebber, Benjamin, Cook, Sally, Graham, Nancy R, Carmolli, Marya, Dickson, Dorothy, Diehl, Sean A, Kirkpatrick, Beth D, Lee, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551743/
https://www.ncbi.nlm.nih.gov/pubmed/34725646
http://dx.doi.org/10.1136/bmjpo-2021-001259
Descripción
Sumario:Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in December 2020. Among 336 students (63%) and 196 teachers/staff (37%), adjusted seroprevalence was 4.7% (95% CI 2.9 to 7.2) and was lowest in preK-5 students (4–10 Years). Seroprevalence was 10-fold higher than corresponding state PCR data but was low overall with no evidence of onward transmissions. These results further support feasibility of in-person learning during COVID-19 with appropriate mitigation measures.