SARS CoV-2 seroprevalence in a US school district during COVID-19

Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in...

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Autores principales: Bullis, Sean S M, Grebber, Benjamin, Cook, Sally, Graham, Nancy R, Carmolli, Marya, Dickson, Dorothy, Diehl, Sean A, Kirkpatrick, Beth D, Lee, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Original Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551743/
https://www.ncbi.nlm.nih.gov/pubmed/34725646
http://dx.doi.org/10.1136/bmjpo-2021-001259
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author Bullis, Sean S M
Grebber, Benjamin
Cook, Sally
Graham, Nancy R
Carmolli, Marya
Dickson, Dorothy
Diehl, Sean A
Kirkpatrick, Beth D
Lee, Benjamin
author_facet Bullis, Sean S M
Grebber, Benjamin
Cook, Sally
Graham, Nancy R
Carmolli, Marya
Dickson, Dorothy
Diehl, Sean A
Kirkpatrick, Beth D
Lee, Benjamin
author_sort Bullis, Sean S M
collection PubMed
description Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in December 2020. Among 336 students (63%) and 196 teachers/staff (37%), adjusted seroprevalence was 4.7% (95% CI 2.9 to 7.2) and was lowest in preK-5 students (4–10 Years). Seroprevalence was 10-fold higher than corresponding state PCR data but was low overall with no evidence of onward transmissions. These results further support feasibility of in-person learning during COVID-19 with appropriate mitigation measures.
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spelling pubmed-85517432021-10-28 SARS CoV-2 seroprevalence in a US school district during COVID-19 Bullis, Sean S M Grebber, Benjamin Cook, Sally Graham, Nancy R Carmolli, Marya Dickson, Dorothy Diehl, Sean A Kirkpatrick, Beth D Lee, Benjamin BMJ Paediatr Open Original Research Letter Reduced symptomatology and access to testing in children have led to underestimates of paediatric COVID-19 prevalence and raised concerns about school safety. To explore COVID-19 prevalence and risk factors in school settings, we conducted a SARS-CoV-2 serosurvey in a Vermont, USA school district in December 2020. Among 336 students (63%) and 196 teachers/staff (37%), adjusted seroprevalence was 4.7% (95% CI 2.9 to 7.2) and was lowest in preK-5 students (4–10 Years). Seroprevalence was 10-fold higher than corresponding state PCR data but was low overall with no evidence of onward transmissions. These results further support feasibility of in-person learning during COVID-19 with appropriate mitigation measures. BMJ Publishing Group 2021-10-27 /pmc/articles/PMC8551743/ /pubmed/34725646 http://dx.doi.org/10.1136/bmjpo-2021-001259 Text en © Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) .
spellingShingle Original Research Letter
Bullis, Sean S M
Grebber, Benjamin
Cook, Sally
Graham, Nancy R
Carmolli, Marya
Dickson, Dorothy
Diehl, Sean A
Kirkpatrick, Beth D
Lee, Benjamin
SARS CoV-2 seroprevalence in a US school district during COVID-19
title SARS CoV-2 seroprevalence in a US school district during COVID-19
title_full SARS CoV-2 seroprevalence in a US school district during COVID-19
title_fullStr SARS CoV-2 seroprevalence in a US school district during COVID-19
title_full_unstemmed SARS CoV-2 seroprevalence in a US school district during COVID-19
title_short SARS CoV-2 seroprevalence in a US school district during COVID-19
title_sort sars cov-2 seroprevalence in a us school district during covid-19
topic Original Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551743/
https://www.ncbi.nlm.nih.gov/pubmed/34725646
http://dx.doi.org/10.1136/bmjpo-2021-001259
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