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Mesenchymal Stem Cells and NF-κB Sensing Interleukin-4 Over-Expressing Mesenchymal Stem Cells Are Equally Effective in Mitigating Particle-Associated Chronic Inflammatory Bone Loss in Mice

Wear particles from total joint arthroplasties (TJAs) induce chronic inflammation, macrophage infiltration and lead to bone loss by promoting bone destruction and inhibiting bone formation. Inhibition of particle-associated chronic inflammation and the associated bone loss is critical to the success...

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Detalles Bibliográficos
Autores principales: Zhang, Ning, Utsunomiya, Takeshi, Lin, Tzuhua, Kohno, Yusuke, Ueno, Masaya, Maruyama, Masahiro, Huang, Ejun, Rhee, Claire, Yao, Zhenyu, Goodman, Stuart B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551755/
https://www.ncbi.nlm.nih.gov/pubmed/34722543
http://dx.doi.org/10.3389/fcell.2021.757830