Ectopic Splicing Disturbs the Function of Xist RNA to Establish the Stable Heterochromatin State

Non-coding Xist RNA plays an essential role in X chromosome inactivation (XCI) in female mammals. It coats the X chromosome in cis and mediates the recruitment of many proteins involved in gene silencing and heterochromatinization. The molecular basis of how Xist RNA initiates chromosomal silencing...

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Detalles Bibliográficos
Autores principales: Matsuura, Ruka, Nakajima, Tatsuro, Ichihara, Saya, Sado, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551810/
https://www.ncbi.nlm.nih.gov/pubmed/34722536
http://dx.doi.org/10.3389/fcell.2021.751154

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551810/
https://www.ncbi.nlm.nih.gov/pubmed/34722536
http://dx.doi.org/10.3389/fcell.2021.751154

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