Cargando…

Silica gel and microwave-promoted synthesis of dihydropyrrolizines and tetrahydroindolizines from enaminones

A wide range of N-(ethoxycarbonylmethyl)enaminones, prepared by the Eschenmoser sulfide contraction between N-(ethoxycarbonylmethyl)pyrrolidine-2-thione and various bromomethyl aryl and heteroaryl ketones, underwent cyclization in the presence of silica gel to give ethyl 6-(hetero)aryl-2,3-dihydro-1...

Descripción completa

Detalles Bibliográficos
Autores principales:	Klintworth, Robin, Morgans, Garreth L, Scalzullo, Stefania M, de Koning, Charles B, van Otterlo, Willem A L, Michael, Joseph P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2021
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551872/ https://www.ncbi.nlm.nih.gov/pubmed/34760023 http://dx.doi.org/10.3762/bjoc.17.170

Ejemplares similares

New syntheses of (±)-tashiromine and (±)-epitashiromine via enaminone intermediates
por: Riley, Darren L, et al.
Publicado: (2016)

Tandem sequential catalytic enantioselective synthesis of highly-functionalised tetrahydroindolizine derivatives
por: Zhang, Shuyue, et al.
Publicado: (2020)

Microwave Assisted Synthesis, Part 1: Rapid Solventless Synthesis of 3-Substituted Coumarins and Benzocoumarins by Microwave Irradiation of the Corresponding Enaminones
por: Al-Zaydi, Khadijah M.
Publicado: (2003)

Tunable Synthesis of Disulfide-Functionalized Enaminones and 1,4-Thiazines via the Reactions of Enaminones and β-Aminoethanethiol
por: Gao, Yong, et al.
Publicado: (2017)

Enaminones in a multicomponent synthesis of 4-aryldihydropyridines for potential applications in photoinduced intramolecular electron-transfer systems
por: Al-Awadi, Nouria A, et al.
Publicado: (2012)

Enaminones in Heterocyclic Synthesis: A Novel Route to Tetrahydropyrimidines, Dihydropyridines, Triacylbenzenes and Naphthofurans under Microwave Irradiation
por: Al-Mousawi, S.M., et al.
Publicado: (2009)

Microwave-Assisted Synthesis of Fluorescent Pyrido[2,3-b]indolizines from Alkylpyridinium Salts and Enaminones
por: Sokolova, Ekaterina A., et al.
Publicado: (2020)

Microwave Assisted Sol-Gel Synthesis of Silica-Spider Silk Composites
por: Giasuddin, Abul Bashar Mohammad, et al.
Publicado: (2019)

A simple, enaminone-based approach to some bicyclic pyridazinium tetrafluoroborates
por: Josefík, František, et al.
Publicado: (2013)

Synthesis, structure, and mechanical properties of silica nanocomposite polyrotaxane gels
por: Kato, Kazuaki, et al.
Publicado: (2015)

Catalyst-free synthesis of 4-acyl-NH-1,2,3-triazoles by water-mediated cycloaddition reactions of enaminones and tosyl azide
por: Yang, Lu, et al.
Publicado: (2018)

Chemistry of the Enaminone of 1-Acetylnaphthalene under Microwave Irradiation Using Chitosan as a Green Catalyst
por: Hassaneen, Huwaida M. E.
Publicado: (2011)

Ionic Conductive Gels for Optically Manipulatable Microwave Stealth Structures
por: Song, Wei‐Li, et al.
Publicado: (2019)

Enaminones as Building Blocks for the Synthesis of Substituted Pyrazoles with Antitumor and Antimicrobial Activities
por: Riyadh, Sayed M.
Publicado: (2011)

Silica gel Catalyzed Synthesis of Quinophthalone Pigments Under Solvent-Free Conditions Using Microwave Irradiation
por: Loghmani-Khouzani, Hossein, et al.
Publicado: (2002)

Metal-free cascade synthesis of unsymmetrical 2-aminopyrimidines from imidazolate enaminones
por: Cui, Xue, et al.
Publicado: (2021)

An intramolecular C–N cross-coupling of β-enaminones: a simple and efficient way to precursors of some alkaloids of Galipea officinalis
por: Doušová, Hana, et al.
Publicado: (2015)

Rapid and Efficient Microwave‐Assisted Friedländer Quinoline Synthesis
por: Bailey, Helen V., et al.
Publicado: (2020)

Site-Selective Reaction of Enaminones and Enamine Esters for the Synthesis of Novel Diverse Morphan Derivatives
por: Hu, Xing-Mei, et al.
Publicado: (2018)

Organocatalytic activation of isocyanides: N-heterocyclic carbene-catalyzed enaminone synthesis from ketones
por: Kim, Jungwon, et al.
Publicado: (2017)

Selectfluor-mediated tandem cyclization of enaminones with diselenides toward the synthesis of 3-selenylated chromones
por: Xia, Ji-Hong, et al.
Publicado: (2023)

Recent Progress of Microwave-Assisted Synthesis of Silica Materials
por: Díaz de Greñu, Borja, et al.
Publicado: (2020)

Computational exploration of the reaction mechanism of the Cu(+)-catalysed synthesis of indoles from N-aryl enaminones
por: Bernardo, Carlos E. P., et al.
Publicado: (2016)

Copper-Catalyzed Coupling of Thioamides and Donor/Acceptor-Substituted Carbenoids: Synthesis of Enamino Esters and Enaminones
por: Pal, Arpan, et al.
Publicado: (2019)

4-Thiazolidinones in Heterocyclic Synthesis: Synthesis of Novel Enaminones, Azolopyrimidines and 2-Arylimino-5-arylidene-4-thiazolidinones
por: Behbehani, Haider, et al.
Publicado: (2012)

Microwave assisted synthesis of triazoloquinazolinones and benzimidazoquinazolinones
por: Mourad, Aboul-Fetouh E, et al.
Publicado: (2007)

Sol-Gel Synthesis of Non-Silica Monolithic Materials
por: Gaweł, Bartłomiej, et al.
Publicado: (2010)

Undirected C-H Bond Activation in Aluminium Hydrido Enaminonates
por: Amadi, Chijioke Kingsley, et al.
Publicado: (2023)

Efficient PPA-SiO(2)-catalyzed Synthesis of β-enaminones Under Solvent-Free Conditions
por: Nisar, Muhammad, et al.
Publicado: (2013)

PIDA-mediated intramolecular oxidative C–N bond formation for the direct synthesis of quinoxalines from enaminones
por: Zhang, Hong, et al.
Publicado: (2019)

Preparation and Characterization of Silica Nanoparticles and of Silica-Gentamicin Nanostructured Solution Obtained by Microwave-Assisted Synthesis
por: Purcar, Violeta, et al.
Publicado: (2021)

Influence of Polarity and Activation Energy in Microwave–Assisted Organic Synthesis (MAOS)
por: Rodríguez, Antonio M, et al.
Publicado: (2015)

Biocatalytic synthesis and ordered self-assembly of silica nanoparticles via a silica-binding peptide
por: Gungormus, Mustafa
Publicado: (2023)

QSAR Study and Molecular Design of Open-Chain Enaminones as Anticonvulsant Agents
por: Garro Martinez, Juan C., et al.
Publicado: (2011)

Sol-Gel Synthesis of Ordered β-Cyclodextrin-Containing Silicas
por: Trofymchuk, Iryna Mykolaivna, et al.
Publicado: (2016)

Iron Oxide Silica Derived from Sol-Gel Synthesis
por: Darmawan, Adi, et al.
Publicado: (2011)

Allosteric Modulation of GABA(A) Receptors by an Anilino Enaminone in an Olfactory Center of the Mouse Brain
por: Heinbockel, Thomas, et al.
Publicado: (2014)

Cyclodextrin-assisted synthesis of tailored mesoporous silica nanoparticles
por: Topuz, Fuat, et al.
Publicado: (2018)

Synthesis of CuO and Cu(3)N Nanoparticles in and on Hollow Silica Spheres
por: Deshmukh, Rupali, et al.
Publicado: (2013)

Assessing Crystallisation Kinetics of Zr Metal–Organic Frameworks through Turbidity Measurements to Inform Rapid Microwave‐Assisted Synthesis
por: Griffin, Sarah L., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r1ohm87n976ek9a321iihn9mlr