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Mass production of human airway-like neutrophils via transmigration in an organotypic model of human airways
Neutrophils are difficult to study, particularly in tissues, due to their short half-life and propensity for activation. We describe an organotypic airway model that uses patient airway fluid to enable the transmigration of blood neutrophils to acquire an airway-like phenotype in order to better und...
Autores principales: | Dobosh, Brian, Giacalone, Vincent D., Margaroli, Camilla, Tirouvanziam, Rabindra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8551927/ https://www.ncbi.nlm.nih.gov/pubmed/34746861 http://dx.doi.org/10.1016/j.xpro.2021.100892 |
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